What is Platelet-Rich Plasma?
A-PRP is a high concentration of platelets surrounded in its own plasma. A small amount of blood is drawn and the red cells are isolated from the platelet-rich plasma. Since the Autologous Platelet-Rich Plasma (A-PRP) is processed from the patient’s own blood, there is virtually no risk of an allergic reaction or rejection. PRP therapies allow for the separation of a patient’s blood through a variety of harvesting techniques to extract a concentration of autologous platelets. These platelets, when activated, release adhesive glycoproteins (fibrin, fibronectin, and vitronectin) and various growth factors. The growth factors and/or cytokines released when the concentrated autologous platelets are activated in soft tissue include:
- Transforming growth factor beta (TGFβ) – cell division and stem cell attraction
- Connective tissue growth factor (wound healing)
- Insulin-like growth factor I & II (ILGF)
- Vascular endothelial growth factor (organ regeneration)
- Epidermal growth factor (EGF)
- Interleuken 8
- Fibroblast growth factor (wound healing/aesthetics)
- Keratinocyte growth factor (wound healing/aesthetics)
Once these proteins and growth factors bind to the cellular receptors of skin tissue (fibroblasts, endothelial cells, and osteoblasts) at the injection point, they activate a variety of intercellular events which help mediate:
- Migration of stem cells to the injection area
- New Cell proliferation
- Production of extracellular matrix proteins
Regeneration occurs within the tissues and fibrils ensues, growth and tissue repair will continue for up to (5) weeks after the injections. The result is promotion of local tissue growth and repair of damaged tissue that is permanent. Contrary to other solutions for the skin such as Botox and Dermal Fillers, PRP is natural (non-synthetic) and will not be reabsorbed or synthesized by bacteria.
Clinically, PRP has been used by oral surgeons, orthopedic surgeons, podiatrists, and plastic surgeons for over 15 years. Over 1,500 hospitals nationwide utilize PRP in medical procedures for a variety of intra-operative procedures. Platelet-rich plasma procedures have also received considerable attention in the popular media because of its use in treating sports injuries in professional athletes.
We combine the CO2 fractional laser resurfacing or microneedling with the PRP application on the surface, to improve surface wrinkles. The PRP can also be injected into the areas of concern. It may also be used for hair regrowth, using direct injection into the scalp. For best results, this is done once a month for three sessions, then repeated every 4-6 months as necessary. We offer two options for PRP treatments…regular concentration of PRP, and 4 times concentration of PRP.
Blood-Derived Growth Factors